Postgraduation Registration Detail

Research Registry No : PRID-00966_V1
Registration Date : 2020-11-18
Thesis Title : The relation of methadone dose and social functioning of Methadone patients in Myanmar
Author Name : Sun Tun
City : Penang
State/ Region : Penang
Field of Thesis : Public Health
Education Status : PhD
Host Department Address : Centre for Drug Research, Universiti Sains Malaysia
Supervisor's Name : Penang
Supervisor's Designation : Penang
Supervisor’s Home Department :
Year of Post Graduation : 2020
Name and Placement of University : Universiti Sains Malaysia
Academic Level : Ph.D/Doctorate
Thesis Notes for Specialty : PhD (Public health)
Abstract : QUALITY OF HEALTH AMONG METHADONE MAINTENANCE TREATMENT (MMT) PROGRAM CLIENTS IN MYANMAR\r\nABSTRACT \r\n\r\n HIV prevalence rate among PWIDs (People who inject drugs) in Myanmar is high at 28.5% based on 2014 IBBS results. More than 13,441 (16% of the estimated 83,000 PWIDs) have been on methadone treatment in 2017. Evaluation of the methadone program is vital for efficient service delivery. This study aimed to understand the context and important treatment factors of methadone maintenance treatment (MMT) program among clients in Myanmar. A total of 210 respondents were recruited through stratified random sampling from five cities in Myanmar where MMT program existed. Several study instruments such as WHO-QOL-BREF questionnaire, Verona Service Satisfaction Scale questionnaire for Methadone Treatment (VSSS-MT) and Addiction Severity Index (ASI) were used. The urine drug test was also conducted to confirm respondents’ drug use status. Study results showed that 45% (n=93) never injected heroin in the last 30 days, while 55.5% (n=116) injected heroin. The average daily methadone dose in this study was 83mg. Thirty-seven percent (n=74/200) had HIV, 16.27% (n=34/209) reported co-infection (HIV/HCV). More than one-third (36.5%, n=76) received high methadone dose (above 80mg), while 63.46% (n=132) received low dose. Higher methadone dose was associated with decreased in heroin use (p=0.034). In reviewing the quality of life (QOL) of the respondents, the total average score of respondents (QOL) was 60.8%; specifically, 60.1% in the physical domain, 63.1% in the psychological domain, 59.9% in the social relation domain, and 60.4% in the environmental domain. Low QOL scores were associated with low methadone service satisfaction. Furthermore, on analysing addiction severity index (ASI), the average ASI scores of the respondents are; Employment (47.4%), Drug use (16.3%), Alcohol (13.5%), Social-family (10.7%), and Legal (10.5%). Higher ASI score reflects the worse situation. Those who did not inject in the last 30 days had lower ASI scores compared to those who injected (p=0.026). The majority (85%, n=178) were highly satisfied with methadone services. More than two-thirds (89.47%, n=187) were highly satisfied with the staff category (doctor, nurse, etc), 91.87%, n=192) on basic intervention items, and 74.64% (n=156) on specific intervention items of the methadone program. Higher methadone dose can reduce the illicit drug injection and subsequently prevent HIV transmissions among individuals who inject drugs. In the estimation of treatment satisfaction of methadone program, the satisfaction of respondent varies with different infection status after taking into consideration of adjustment of methadone dose. Since poly-drug use was prevalent, other harm reduction measures are seen important to prevent the risk of addiction and infectious diseases. Continuous treatment assessments are vital for identifying challenging areas like special service categories of MMT program (e.g individual rehabilitation, psychotherapy and group therapy) and support for HIV/HCV co-infections are needed to ensure effective service delivery. \r\n
IRB/PRC/ERC Approval Date : 2017-04-24
Placement of IRB/PRC/ERC : Department of Medical Research, Yangon, Myanmar
IRB/PRC/ERC Approval Letter/PRC/Document : 18112020073111MyanmarERCPermission3.5.2017.pdf
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