Preliminary Registration Detail

Research Registry No : PLRID-00644_V2
Postgraduate Research : No
University Departmental Research : Yes
Name of University : Yangon General Hospital
Department : Tropical and Infectious Diseases
Registration Date : 2020-02-25
Principle Investigator : MOE MOE SAN
Co-Investigators : Faye Callaghan
Title of Research : Antibiotic Prescribing audit as Part of the Establishment of an Antimicrobial Stewardship Programme in Yangon General Hospital
Field of Research : Tropical and Infectious Diseases
Preliminary Research Design : Descriptive Study
Preliminary Research Type : Applied
Preliminary Justification : Antimicrobial resistance (AMR) is one of the biggest healthcare threats mankind faces with the potential to result in 10 million deaths annually worldwide by 2050 if left unchallenged1. The World Health Organisation launched its Global Action Plan on Antimicrobial Resistance2 at the 68th World Health Assembly in May 2015, providing a framework for national plans. In response, the Myanmar Government produced a National Action Plan on Antimicrobial Resistance 2017-20223. Hospital level antimicrobial stewardship is core to the achievement of the plan’s goals. Improvement of antimicrobial stewardship at Yangon General Hospital plays a part in successful implementation of the Myanmar National Action Plan for Containment of Antimicrobial Resistance 2017-2022. This will be achieved through: - Introduction of an Antimicrobial Stewardship Committee - Production of a three-year antimicrobial stewardship plan - Implementation of plan activities which align with the national action plan objectives, including an audit of antibiotic prescribing. An ongoing collaboration between the Brighter Future Foundation and Health Education England, and Yangon General Hospital, a project focused on Antimicrobial Stewardship Programme has been implemented in Yangon General Hospital. The work involves a proposal to establish an AMS committee, produce a hospital specific antibiotic prescribing guideline, antibiotic ward round and Doctor-led7 audits of antibiotic prescribing in two wards (Medical Unit II B and Tropical and Infectious Diseases). On March, 2019, a small-scale preliminary antibiotic prescribing audit was conducted in two medical wards of YGH, MU2B and Tropical and infectious diseases department. From this intradepartmental audit, antibiotic prescribing pattern of two medical wards can be predicted and it is the initiative to promote the YGH antimicrobial stewardship programme. However, this audit was a small-scale pilot study which was conducted in a short period. Therefore, it is needed to implement further large-scale long period antibiotic audit in YGH to evaluate more data of antibiotic prescribing pattern.
Preliminary Aim : • To implement antibiotic prescription audit as part of the establishment of an antimicrobial stewardship programme in Yangon General Hospital
Preliminary Objectives : • To find out the antibiotic prescribing pattern among in patients of two medical wards of YGH ( MU2B and Tropical and infectious diseases ward) • To serve as input for establishing the part of antimicrobial stewardship in YGH
Preliminary Sample Size : Random sampling of 10 drug charts will be done from each ward on every fourth day of post admission. Twenty drug charts will be reviewed per each week and over three month period, total 240 drug charts will be audited.
Preliminary Study Duration : 3 months
Preliminary Study Area : Department of Tropical and Infectious Diseases and Medical Unit 2B, Yangon General Hospital.
Preliminary Study Method : - Standards to audit against will be agreed and in line with WHO recommendations. - On day four after admission, an assigned doctor will pick a random bed number by lottery method. - They will audit that chart (can be male or female) and collect the data. - The top right corner of the drug chart will be marked with ‘A’ when done, to avoid duplication. - The next chart will be selected by counting forward five beds, taking that chart and auditing it. This process will be repeated until ten charts have been audited. - Charts will be rejected if they have already been audited or the patient is not prescribed antibiotics. - Corrective action plan will be carried out for further decision to handle the necessities. - Charts reviewing, auditing and data collection will be done by trained medical doctors from each ward, - Trained doctors from each ward will be switched to avoid prejudices. - Data collection sheet and algorithm are attached in annex. - No patient identifiable information will be recorded. Notes will not be removed from the ward during the period of the audit.
Preliminary Research Outcome : Ongoing
Preliminary Research Finding : Ongoing
Preliminary Progress Report : Ongoing
Study Starting Date : 2020-03-01
IRB/PRC/ERC Approval Date : 2020-01-31
Placement of IRB/PRC/ERC : Department of Tropical and Infectious Diseases
IRB/PRC/ERC Approval Letter/Document : 250220200553272019-145ProfessorMoeMoeSan.pdf
Pre-existing Registration ID : None
Pre-existing Name of Organization : -
Pre-existing Name of Organization Website : -