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Research Registry No |
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PLRID-00654_V1 |
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Postgraduate Research |
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local |
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Name of University |
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University Of Dental Medicine, Mandalay |
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Degree |
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B.D.S |
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University Departmental Research |
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Yes |
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Name of University |
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University of Dental Medicine, Mandalay |
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Department |
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Department of Paediatric Dentistry |
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Registration Date |
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2020-02-24 |
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Principle Investigator |
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Kyi Wai |
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Co-Investigators |
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Dr. Zayyar Maung |
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Title of Research |
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EFFECTIVENESS OF REGENERATIVE ENDODONTIC PROCEDURE IN THE TREATMENT OF NECROTIC IMMATURE PERMANENT TEETH |
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Field of Research |
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Dentistry |
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Preliminary Research Design |
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Experimental Study |
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Preliminary Research Type |
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Applied |
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Preliminary Justification |
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Regenerative endodontic procedure is a biologically based procedures designed to replace damaged structures such as dentin, root structures, and cells of the pulp-dentin complex. It is also a common category of biologically based endodontic therapy known as revascularization or revitalization. This treatment modality aims to promote normal pulpal physiologic functions and to regenerate the components and normal function of pulp-dentine complex.
Many benefits can be observed in revascularization procedure by induced bleeding. This procedure is simple, practical and low-cost procedure. The possibility of immune rejection and pathogen transmission are very minimal since regeneration occurs by patient’s own biological tissue. Due to the obturation of root canal is not required, it eliminates the chance of fracture due to condensation pressure. Major advantage is continued root development and there is reinforcement of lateral dentinal walls with deposition of new dentine and apical closure.
For the time being, there is very limited study related with regenerative endodontic therapy. This research may fulfill partly and gives some more information what will happened after procedure in future.
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Preliminary Aim |
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The aim of this study is to evaluate the effectiveness of regenerative endodontic procedure in the treatment of necrotic immature permanent teeth. |
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Preliminary Objectives |
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1. To evaluate the clinical success rates of regenerative endodontic procedure at 6 months and 9 months 2. To assess the radiographic outcomes of root development, dentinal wall thickness, and apical closure at 6 months and 9 months by comparing with baseline radiographic features |
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Preliminary Sample Size |
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15 necrotic immature permanent teeth |
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Preliminary Study Duration |
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One year (September, 2018 to August, 2019) |
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Preliminary Study Area |
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Department of Paediatric Dentistry, University of Dental Medicine, Mandalay |
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Preliminary Study Method |
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Quasi experimental study |
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Preliminary Research Outcome |
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Regenerative endodontics is a hopeful alternative treatment for necrotic immature permanent teeth. However, the success and timing of clinical resolution of symptoms, and radiographic outcomes of interest, such as continued hard tissue deposition within t |
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Preliminary Research Finding |
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the findings reported here support the idea that regenerative endodontic procedures have a high clinical success rate and this procedure also induced in root length, thickness, and apical closure. However, histologic studies on human revascularized teeth |
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Preliminary Progress Report |
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Progressing in writing |
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Study Starting Date |
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2018-08-01 |
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IRB/PRC/ERC Approval Date |
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2018-08-31 |
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Placement of IRB/PRC/ERC |
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University of dental medicine, Mandalay, Ethical and Research committee |
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IRB/PRC/ERC Approval Letter/Document |
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24022020145610KyiWaiApproval.pdf |
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Pre-existing Registration ID |
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no |
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Pre-existing Name of Organization |
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no |
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Pre-existing Name of Organization Website |
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no |