Health Research Registry List

Research Registry No : HRID-00040_V8
University Departmental Research :
Registration Date : 2019-08-15
Title of Research : Sustainable access to Primaquine in malaria endemic areas: Health system bottlenecks and best practices at pre-elimination era, Myanmar
Principle Investigator : KAY THWE HAN
Co-authors : Aung Thi, Khin Thet Wai,Tin Oo, Zayar Han, Kyin Hla Aye, Aung Ye Naung Win
Field of Research : Public Health
Publication Source : Han et al. Tropical Medicine and Health (2018) 46:32
Year of Publication : 2018
URL of Publication :
Presentation Source : 47th Myanmar Health Research Congress,2019: p 140-141
Placement of Presentation : DMR
Year of Presentation : 2019
Abstract : Access to primaquine in the last mile: challenges at the service delivery points in pre-elimination era, Myanmar Kay Thwe Han, Khin Thet Wai, Tin Oo, Aung Thi, Zayar Han , Kyin Hla Aye, Aung Ye Naung Win and Jetsumon Sattabongkot Prachumsri Abstract Background: Alongside monitoring of the disease burden, the successful move towards malaria elimination relies on the readiness of the health care delivery system. However, there is a lack of evidence in the gap of existing National Guidelines and access to low dose primaquine in real practice in the pre-elimination phase in Myanmar. Therefore, this study addressed the essential information from the service delivery points (SDPs) of public and private sectors on the availability and the use of primaquine in both supply and demand side. Concomitantly, the study aimed to underscore challenges in health system infrastructure to promote the sustained flow in rolling out primaquine in line with National Guidelines for malaria elimination. Methods: A cross-sectional study conducted from September 2017 to February 2018 included six townships of three States/Regions. The team used an observation checklist for documenting primaquine supplies at SDPs. Semi-structured interviews, key informant, and in-depth interviews focused both private and public sectors including staff from the National Malaria Control Program (NMCP) teams and rural health centers (n = 25), those from the non-governmental organizations (NGOs), general practitioners and drug sellers (n = 11), and recently infected malaria patients (n = 11). Triangulation of quantitative and qualitative data provided meaningful interpretations. Results: Public sector staff reported an adequate stock of primaquine, but it was unavailable at the general clinics without any connection to NGOs and also at the drug shops. Health care providers of the public sector experienced challenges in poor compliance of vivax malaria patients to primaquine treatment, loss-to-follow-ups especially in conflict areas, and delays in timely substitution of new batches of primaquine. Respondents from the private sector demanded for the refresher training on updated antimalarial treatment guidelines. Volunteers also demanded to let them practice shorter course regimen of primaquine. Conclusion: Monitoring compliance and safety of primaquine treatment was found as a barrier especially among mobile migrant workers and those who were in conflict areas. An alternative strategy by the NMCP could enable to promote primaquine utilization in vivax malaria to reach the malaria elimination targets. Keywords: Primaquine, Sustained access, Service delivery points, Antimalarial treatment guidelines, Pre-elimination, Myanmar
IRB/PRC/ERC Approval Date : 2018-07-02
Placement of IRB/PRC/ERC : DMR
IRB/PRC/ERC Approval Letter/Document : PMQ ERC.pdf
Pre-existing Registration ID : -
Pre-existing Name of Organization : -
Pre-existing Website : no