Health Research Registry List

Research Registry No : HRID-00187_V5
 
University Departmental Research :
 
Registration Date : 2019-05-17
 
Title of Research : Detection of birth defects among newborns at seven tertiary hospitals in Yangon Region
 
Principle Investigator : Mya Ohnmar
 
Co-authors : Khin Mittar Moe San, Nway Htike Maw, Moh Moh Hlaing, Sandar Tun, Myat Myat Thu and Khin Hnin Wint Ph
 
Field of Research : Nutrition
 
Publication Source :
 
 
Year of Publication : -
 
URL of Publication : -
 
Presentation Source : Presentation of a research paper at the 46th Myanmar Health Research Congress
 
Placement of Presentation : DMR
 
Year of Presentation : 2018
 
Abstract : Birth defects are one of the most common causes of disability in developed and developing countries. Birth defects are structural or functional anomalies, including metabolic disorders, which are present at the time of birth. This study aimed to document the overall frequency and pattern of birth defects of newborns delivered in seven hospitals in Yangon region. The study was a retrospective, hospital-record review study to find the prevalence of birth defect in newborns at seven tertiary hospitals during the period of January 2014-December 2015 in Yangon Region. Seven hospitals in Yangon Region where both OG wards and baby units are co-existed, were selected purposively. The selected hospitals were Central Women’s Hospital (CWH), Thingankyun Sanpya General Hospital, South Okkalapa Women and Children’s Hospital, North Okkalapa General Hospital (NOGH), Insein General Hospital (IGH), East Yangon General Hospital and West Yangon General Hospital. Cases with birth defects were identified from the birth registry and the corresponding files were retrieved from the hospital medical records section. The details were recorded in the designed proforma. During the study period, the incidence of birth defect in CWH, Thingankyun Sanpya General Hospital, South Okkalapa Women and Children’s Hospital, NOGH, IGH, East Yangon General Hospital and West Yangon General Hospital were 1.21%, 0.99%, 0.57%, 0.45%, 0.17%, 0.33% and 0.21% in 2014 and 1.11%, 0.93%, 0.54%, 0.88%, 0.5%, 0.48% and 1.49% in 2015, respectively. Of these, multi-organ defect (21.7%) were the commonest, followed by central nervous system (15.9%), cleft lip and cleft palate (15.5%), musculo-skeletal system(14.3%) and gastrointestinal tract (13.6%) in 2014. In 2015, multi-organ defects (20.17%) were also commonest, followed by muscular-skeletal system (19%), central nervous system (17.8%), cleft lip and cleft palate (14.1%) and gastrointestinal tract (7.9%). There was increase in incidence of birth defect in NOGH, IGH, East Yangon General Hospital and West Yangon General Hospital and according to system defect, muscular-skeletal system, central nervous system defect were increasing in 2015. This study helps define the burden of birth defects in the Yangon Region. There is a need for more extensive, nationwide studies to determine the birth prevalence, types and distribution of birth defects in Myanmar.
 
 
IRB/PRC/ERC Approval Date : 2016-06-01
 
Placement of IRB/PRC/ERC : DMR
 
IRB/PRC/ERC Approval Letter/Document : birth defect .pdf
 
Pre-existing Registration ID : -
 
Pre-existing Name of Organization : -
 
Pre-existing Website : -