Health Research Registry List

Research Registry No : HRID-00565_V2
University Departmental Research : No
Registration Date : 2020-03-13
Title of Research : School-based soil-transmitted Helminthiasis Prevalence in Myanmar(2019)
Principle Investigator : SOE MIN OO
Co-authors : Aung Tun
Field of Research : Public Health
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Abstract : Soil-transmitted helminth (STH) infections have been the most common infections among the school-aged children(SAC) globally. After launching the routine school-based mass drug administration(MDA) throughout Myanmar in 2005, the survey findings in 2012 has indicated the possibility to reduce deworming frequency though there was no updated data. This nationwide cross-sectional study aimed to determine the prevalence and intensity of STH infection and nutritional status among SAC after 14 years of MDA. A total of 1039 SAC were recruited from twenty schools of four townships from August to December 2019. Each township was selected from four geographical areas; hilly, plain, delta, and coastal. We used Stata 15.0 for data analysis. Our research findings indicated STH infections was virtually absent in the hilly area but continued to be endemic with many variations of prevalence and intensity; the delta area with the highest roundworm infection and whipworm reinfection, the coastal area with roundworm reinfection, and the plain area with hookworm reinfection (p value<0.001). On multivariable logistic regression after adjustment of age and sex, SAC living in the hilly area were less likely to get STH infection (OR = 0.56; 95%CI: 0.46 to 0.69). The burden of underweight and anemia was high in the delta and the coastal (p value<0.001). Regular school-based MDA can be reduced to once a year basis in the hilly area, however, the present twice a year frequency needs to be sustained in the rest areas. Likewise, triple-dose deworming regimens should be considered in the delta area to eliminate whipworm reinfection. Keywords: Soil-transmitted helminth infections, underweight, anemia, Myanmar
IRB/PRC/ERC Approval Date : 2019-08-23
Placement of IRB/PRC/ERC : UPH-IRB
IRB/PRC/ERC Approval Letter/Document : 13032020060558UPH-IRB(2019IRResearch16)Dr.SoeMinOo.pdf
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